Fexofenadine (often sold as Allegra) is a popular non-drowsy antihistamine for seasonal allergies. People like it because it usually causes less sleepiness than older antihistamines. Still, no drug is risk-free—this page gives straightforward, useful safety info so you can use it smartly.
Most people tolerate fexofenadine well. The common side effects are mild: headache, dry mouth, nausea, or mild fatigue. These usually go away after a few days. If you notice fast heartbeat, severe dizziness, or a rash with swelling of the face or throat, treat it like an emergency and get medical help right away—those are signs of a serious reaction.
If your allergy symptoms don't improve or they suddenly get worse after starting fexofenadine, call your doctor. Also speak up if you feel more tired than usual, since individual response varies.
Some simple things reduce how well fexofenadine works. Don't take it with fruit juices like orange, apple, or grapefruit at the same time—these juices can cut how much drug your body absorbs. Antacids that contain aluminum or magnesium can also lower fexofenadine levels if swallowed together; separate them by a few hours.
Avoid mixing fexofenadine with other sedating drugs or alcohol if you feel drowsy—while fexofenadine is labeled "non-drowsy," combining medicines can change how you feel. If you take many medications or have liver or kidney disease, check with your healthcare provider before using fexofenadine. People with severe kidney problems may need a lower dose.
Pregnancy and breastfeeding: there’s limited data on fexofenadine in pregnancy and breast milk. If you’re pregnant, planning pregnancy, or breastfeeding, talk to your clinician about whether this medicine is right for you.
Start with the smallest recommended dose that controls your symptoms and follow the label or your doctor’s instructions. For kids, use the age-appropriate form and dose—never give adult-strength tablets to young children. Store medicine out of reach of children and follow expiry dates.
Keep a short list of your current meds and show it to any new provider. If you need surgery or a new prescription, mention you take fexofenadine. For travel, pack a copy of the medication label and your doctor’s contact in case you need advice while away.
If you suspect an overdose, call your local emergency number or poison control immediately. For ongoing questions—side effects, mixing with other drugs, or using it during pregnancy—talk to your pharmacist or doctor. Simple checks now can prevent bigger problems later.
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